evidence from human and animal studies // Int J Obes (Lond). 2016 Mar;40(3):381-94 // doi: 10.1038/ijo.2015.177.
Williams S. E., et al. ASPM sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice // Development. 2015. Nov. 15. Vol. 142. No. 22. Pp. 3921–3932 // doi: 10.1242/dev.124271.
Chakravarthy MV, Booth FW. Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases // J Appl Physiol (1985). 2004 Jan;96(1):3-10 // doi: 10.1152/japplphysiol.00757.2003.
Mathias Rask-Andersen, et al. Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status // PLOS Genetics, 2017; 13 (9): e1006977 // DOI: 10.1371/journal.pgen.1006977.
Mao L., et. al. Population differentiation in allele frequencies of obesity-associated SNPs // BMC Genomics. 2017. Nov. 10. Vol. 18. No. 1. P. 861 // doi: 10.1186/s12864-017-4262-9.
McClure AC, et al. Receptivity to television fast-food restaurant marketing and obesity among U.S. youth // Am J Prev Med. 2013 Nov;45(5):560-8 // doi: 10.1016/j.amepre.2013.06.011; phttps://pubmed.ncbi.nlm.nih.gov/24139768/.
Gilbert-Diamond D., Emond J. A., Lansigan R. K. et al. Television food advertisement exposure and FTO rs9939609 genotype in relation to excess consumption in children // Int. J. Obes. (Lond). 2017. Jan. Vol. 41. No. 1. Pp. 23–29 // doi: 10.1038/ijo.2016.163.
Kilpeläinen T. O., et al. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children // PLoS Med. 2011. Nov. Vol. 8. No. 11. P. e1001116 // doi: 10.1371/journal.pmed.1001116; Xiang L., Wu H., Pan A. et al. FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis // Am. J. Clin. Nutr. 2016. Apr. Vol. 103. No. 4. Pp. 1162–1170 // doi: 10.3945/ajcn.115.123448.
Graff M., et al. Genome-wide physical activity interactions in adiposity — A meta-analysis of 200,452 adults // PLoS Genet. 2017. Apr. 27. Vol. 13. No. 4. P. e1006528 // doi: 10.1371/journal.pgen.1006528.
de Luis D. A., et al. RS9939609 FTO gene variant modified weight loss and insulin resistance after a partial meal-replacement hypocaloric diet // Eur. Rev. Med. Pharmacol. Sci. 2020. May. Vol. 24. No. 10. Pp. 5573–5581 // doi: 10.26355/eurrev_202005_21343.
Samaan Z., et al. The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression // Mol. Psychiatry. 2013. Dec. Vol. 18. No. 12. Pp. 1281–1286 // doi: 10.1038/mp.2012.160; Samaan Z, et al. The protective effect of the obesity-associated rs9939609. A variant in fat mass- and obesity-associated gene on depression // Mol Psychiatry. 2013 Dec;18(12):1281-6 // doi: 10.1038/mp.2012.160; Roetker NS, et al. Multigene interactions and the prediction of depression in the Wisconsin Longitudinal Study // BMJ Open. 2012 Jul 2;2(4):e000944 // doi: 10.1136/bmjopen-2012-000944.
Melnik B. C. Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases // J. Transl. Med. 2015. Dec. 21. Vol. 13. P. 385 // doi: 10.1186/s12967-015-0746-z; Melnik BC, Schmitz G. Exosomes of pasteurized milk: potential pathogens of Western diseases // J Transl Med. 2019 Jan 3;17(1):3 // doi: 10.1186/s12967-018-1760-8; Melnik BC, John SM, Schmitz G. Adipogenic and insulin resistance-promoting effects of milk consumption // Mol Nutr Food Res. 2014 Jun;58(6):1166-7 // doi: 10.1002/mnfr.201470054.
Azushima K., Tamura K., Wakui H. et al. Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity // PLoS One. 2013. Oct. 9. Vol. 8. No. 10. P. e75560 // doi: 10.1371/journal.pone.0075560.
Hibbard E. D., Smithells R. W. Folic acid metabolism and human embryopathy // Lancet. 1965. Vol. i. P. 1254 // academic.oup.com/ije/article/40/5/1154/660590; Smithells R. W., Shephard S., Schorah C. J. et al. Possible prevention of neural-tube defects by periconceptional vitamin supplementation // Lancet. 1980. Vol. i. Pp. 339–340.
Yafei W., Lijun P., Jinfeng W., Xiaoying Z. Is the prevalence of MTHFR C677T polymorphism associated with ultraviolet radiation in Eurasia? // J. Hum. Genet. 2012. Dec. Vol. 57. No. 12. Pp. 780–786 // doi: 10.1038/jhg.2012.113.
Abhinand P. A., Shaikh F., Bhakat S. et al. Insights on the structural perturbations in human MTHFR Ala222Val mutant by protein modeling and molecular dynamics // J. Biomol. Struct. Dyn. 2016. Vol. 34. No. 4. Pp. 892–905 // doi: 10.1080/07391102.2015.1057866.
Shea Larroque. MTHFR Genetics // medium.com/@sheamatthewfisher/mthfr-genetics-5747d04bb00c.
Zuin M., et al. Elevated Blood Homocysteine and Risk of Alzheimer’s Dementia: An Updated Systematic Review and Meta-Analysis Based on Prospective Studies // J. Prev. Alzheimers Dis. 2021. Vol. 8. No. 3. Pp. 329–334 // doi: 10.14283/jpad.2021.7.
Chaudhry S. H., et al. The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort // BMC Pregnancy Childbirth. 2019. Feb. 19. Vol. 19. No. 1. P. 75 // doi: 10.1186/s12884-019-2219-5.
Mouhamed D. H., et al. Effect of cigarette smoking on plasma homocysteine concentrations // Clin. Chem. Lab. Med. 2011. Mar. Vol. 49. No. 3. Pp. 479–483 // doi: 10.1515/CCLM.2011.062; Verhoef P., et al. Contribution of caffeine to the homocysteine-raising effect of coffee: a randomized controlled trial in humans // The American Journal of Clinical Nutrition. 2002. Dec. Vol. 76. No. 6. Pp. 1244–1248 // doi: 10.1093/ajcn/76.6.1244.
Robinson J. L., et al.
