Wu J, Gu M, Chen S, et al. Factors related to pediatric obstructive sleep apneahypopnea syndrome in children with attention deficit hyperactivity disorder in different age groups. Medicine. 2017;96(42):e8281. doi: 10.1097/MD.0000000000008281
Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013; 342(6156):373–377. doi: 10.1126/science.1241224
Yaffe C, Laffan AM, Harrison SL, et al. Sleep disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. J Am Med Assoc. 2011;306(6):613–619. doi: 10.1001/jama.2011.1115
Youssef NA, Ege M, Angly SS, Strauss JL, Marx CE. Is obstructive sleep apnea associated with ADHD? Ann Clin Psychiatry. 2011;23(3):213–224.
Zetterberg H, Mortberg E, Song L, et al. Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans. PLoS One. 2011;6(12):e28263. doi: 10.1371/journal.pone.0028263
Chapter 7. Metabolic and Vitamin Deficiencies
Balion C, Griffith LE, Strifler L, et al. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology. 2012;79(13);1397–1405. doi: 10.1212/WNL.0b013e31826c197f
Bauer SR, Kapoor A, Rath M, Thomas SA. What is the role of supplementation 240 For Further Reading with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? Cleve Clin J Med. 2020 Jun 8. doi: 10.3949/ccjm.87a.ccc046
Beydoun MA, Beydoun HA, Gamaldo AA, Teel A, Zonderman AB, Wang Y. Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis. BMC Public Health. 2014;14(643). doi: 10.1186/1471-2458-14-643
Bjelakovic G, Gluud L, Nikolova D, et al. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst Rev. 2014, 1(CD007470). doi: 10.1002/14651858.CD007470.pub3
Blasko I, Hinterberger M, Kemmlesr G, et al. Conversion from mild cognitive impairment to dementia: influence of folic acid and vitamin B12 use in the vita cohort. J Nutr Health Aging. 2012;16(8):687–694. doi: 10.1007/s12603-012-0051-y
Buell JS, Dawson-Hughes B, Scott TM, et al. 25-hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology. 2010;74(1):18–26. doi: 10.1212/WNL.0b013e3181beecb7. Epub 2009 Nov 25.
Camaschella C. Iron-deficiency anemia. N Eng J Med. 2015;372(19):1832–1843. doi: 10.1056/NEJMra1401038
Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol. 1998;55(11):1449–1455. doi: 10.1001/archneur.55.11.1449
Clemens TL. Vitamin B12 deficiency and bone health. N Eng J Med. 2014;371:963–964. doi: 10.1056/NEJMcibr1407247
Council for Responsible Nutrition. Dietary supplement use reaches all time high. www.crnusa.org/newsroom/dietary-supplement-use-reaches-all-time-high#
Dash P, Hergenroeder G, Jeter C, Choi H, Kobori N, Moore A. Traumatic brain injury alters methionine metabolism: implications for pathophysiology. Front Syst Neurosci. 2016.10:36. doi: 10.3389/fnsys.2016.00036
Ebly EM, Schaefer JP, Campbell NR, Hogan DB. Folate status, vascular disease and cognition in elderly Canadians. Age Ageing. 1998;27(4):485–491. doi: 10.1093/ageing/27.4.485
Ganji V, Kafai MR. Population references for plasma total homocysteine concentrations for U.S. children and adolescents in the post-folic acid fortification era. J Nutr. 2005;135(9):2253–2256. doi: 10.1093/jn/135.9.2253
Geisel T, Martin J, Schulze B, et al. An etiologic profile of anemia in 405 geriatric For Further Reading 241 patients. Anemia. 2014;932486. doi: 10.1155/2014/942486. Epub 2014 Feb 23.
Giles WH, Croft JB, Greenlund KJ, Ford ES, Kittner SJ. Total homocyst(e)ine concentration and the likelihood of nonfatal stroke: results from the Third National Health and Nutrition Examination Survey, 1988–1994. Stroke. 1998;29(12):2473–2477. doi: 10.1161/01.str.29.12.2473
Goss AM, Gower B, Soleymani T, et al. Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity: a randomized clinical trial. Nutri Metab. 2020;17(64). doi: 10.1186/s12986-020-00481-9
Hannibal L, Lysne V, Bjørke-Monsen A-L, et al. Biomarkers and algorithms for the diagnosis of vitamin B12 deficiency. Front Mol Biosci. 2016;3.27. doi: 10.3389/fmolb.2016.00027
Haan MN, Miller JW, Aiello AE, et al. Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging. Am J Clin Nutr. 2007;85(2):511–517. doi: 10.1093/ajcn/85.2.511
Harkin A. Muscling in on depression. N Eng J Med. 2014;371:2333–2334. doi: 10.1056/NEJMcibr1411568
Hicks GE, Shardell M, Miller RR, et al. Associations between vitamin D status and pain in older adults: The Invecchiare in Chianti Study. J Am Geriatr Soc. 2008;56:785–791. doi: 10.1111/j.1532–5415.2008.01644.x
Ho PI, Ortiz D, Rogers E, Shea TB. Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J Neurosci Res. 2002;70(5):694–702. doi: 10.1002/jnr.10416
Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006; 81(3):353–373. doi: 10.4065/81.3.353
Holland TM, Agarwal P, Wang Y, et al. Dietary flavonols and risk of Alzheimer dementia. Neurology. 2020;94(16):e1749–e1756; doi: 10.1212/WNL.0000000000008981
Jáuregui-Lobera I. Iron deficiency and cognitive functions. Neuropsychiatr Dis Treat. 2014;10(10):2087–2095. doi: 10.2147/NDT.S72491
Jochemsen HM, Kloppenborg RP, de Groot LC, et al. Homocysteine, progression of ventricular enlargement, and cognitive decline: the Second Manifestations of Arterial Disease-Magnetic Resonance Study. Alzheimers Dement. 2013;9(3):302–309. doi: 10.1016/j.jalz.2011.11.008. Epub 2012 Aug 3. 242 For Further Reading
Kang JH, Cook N, Manson J, Buring JE, Albert CM, Grodstein F. A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease.
Am J Clin Nutr. 2008;88(6):1602–1610. doi: 10.3945/ajcn.2008.26404
Köhnke C, Herrmann M, Berger K. Associations of major depressive disorder and related clinical characteristics with 25-hydroxyvitamin D levels in middle-aged adults. Nutr Neurosci. 2020;9:1–10. doi: 10.1080/1028415X.2020.1843892. Epub ahead of print.
Lipton SA, Kim WK, Choi YB, et al. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci USA. 1997;94(11):5923–5928. doi: 10.1073/pnas.94.11.5923
Llewellyn DJ, Lang IA, Langa KM, et al. Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med. 2010;170(13):1135–1141. doi: 10.1001/archinternmed.2010.173
Malinow MR, Bostom AG, Krauss RM. Homocyst(e)ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation. 1999 Jan 5–12;99(1):178–182. doi: 10.1161/01.cir.99.1.178
Masoumi A, Goldenson B, Ghirmai S, et al. 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer’s disease patients. J Alzheimers Dis. 2009;17(3):703–717. doi: 10.3233/JAD-2009-1080
Mizwicki MT, Menegaz D, Zhang J, et al. Genomic and nongenomic signaling induced by 1α,25(OH)2-vitamin D3 promotes the recovery of amyloid-β phagocytosis by Alzheimer’s disease macrophages. J Alzheimers Dis. 2012;29(1):51–62. doi: 10.3233/JAD-2012-110560
Mujica-Parodi LR, Amgalan A, Sultan SF, et al. Diet modulates brain network stability, a biomarker for brain aging, in young adults. Proc Natl Acad Sci. 2020;117(11):6170–6177; doi: 10.1073/pnas.1913042117
